三级在线看中文字幕完整版,人妻熟妇乱又伦精品视频app,偷偷色噜狠狠狠狠的777米奇,a级毛片免费观看在线

首頁 >> 產(chǎn)品展示 >> 抗體 >> chromotek代理商 >> Chromotek/F2H®-Kit Androgen Receptor

Chromotek/F2H®-Kit Androgen Receptor

簡要描述:Chromotek/F2H®-Kit Androgen Receptor Analyze modulators of the human Androgen Receptor
  Detect early steps of Androgen Receptor activation

  • 產(chǎn)品型號:
  • 廠商性質(zhì):經(jīng)銷商
  • 更新時(shí)間:2018-01-22
  • 訪  問  量:1431
詳細(xì)資料

Chromotek/F2H®-Kit Androgen Receptor

 螞蟻淘介紹:

螞蟻淘,【正品極速】生物醫(yī)學(xué)科研用品輕松購

螞蟻淘(ebiomall)是一家生命科學(xué)領(lǐng)域的垂直電商平臺,公司專注生物醫(yī)學(xué)科研用品的  導(dǎo)購和品牌推廣,為海外廠方與國內(nèi)代理經(jīng)銷商搭建跨境貿(mào)易系統(tǒng)和交流平臺。

    產(chǎn)品齊全,200+分類,1000+品牌,500+產(chǎn)品信息。100%正品,專業(yè)售后,到貨快,在線下單, 簡單輕松,節(jié)省科學(xué)家寶貴的科研時(shí)間。

借助互聯(lián)網(wǎng)平等而開放的力量,矢志實(shí)現(xiàn)生命科學(xué)領(lǐng)域的信息同步,我們相信一群充滿夢想的人,可以憑借著專業(yè)與執(zhí)著,讓你的購物更輕松!

Chromotek/F2H®-Kit Androgen Receptor

  Analyze modulators of the human Androgen Receptor

  Detect early steps of Androgen Receptor activation

  Visualized in live mammalian cells

  Real-time agonists and antagonists screening

  Convenient readout using an epi-fluorescence microscope

  The human Androgen receptor (AR) is an important target for developing drug therapies combating prostate cancer. The very early event in AR activation, namely the intramolecular interaction between the N- and C-terminus of AR, can now be analyzed with the ChromoTek Fluorescent-Two Hybrid (F2H®) AR: wild-type (wt), as well as several mutant AR forms can be investigated.

Chromotek/F2H®-Kit Androgen Receptor  

Assay principle:

  AR is expressed as two separate domains: AR-LBD (ligand binding domain), comprising the AR’s C-terminus, either wt or mut, fused to GFP: AR-LBD-GFP

  AR-NTD (N-terminal domain), comprising the AR’s N-terminus, fused to RFP: AR-NTD-RFP

  F2H®-BHK cells express components of the protein-protein interaction platform, which recruits GFP-tagged AR-LBD to a specific location in the nucleus

  AR-LBD-GFP and AR-NTD-RFP constructs are co-transfected into the F2H®-BHK cells

  AR-LBD-GFP forms a bright green spot at the specific location in the nuclei whereas AR-NTD-RFP is diffusely distributed in the nucleus

  Upon stimulation by an agonist (e.g. DHT), immobilized AR-LBD-GFP undergoes a conformation change and recruits AR-NTD-RFP: AR-NTD-RFP forms a bright red spot superimposed with the green spot.

  Results:

  Green spot is present, red spot is absent => assay works: no interaction

  Green spot is present, red spot is present at the same location => assay works: interaction

  

 

  Figure: AR-LBD-GFP (top left) forms bright green spots at the genetic Platform in nuclei of F2H-BHK cells. Before addition of DHT, AR-NTD-RFP (bottom left) is dispersed in the nuclei. Upon 20 min incubation with 10nM DHT, the red spots appear (bottom right, arrows) at the location of the green spots, indicating induction of the interaction between AR-LBD and AR-NTD.

  Reversible Screening:

  The F2H AR assay is fully reversible: the AR wt interaction can be induced by an agonist (e.g. 0.25nM DHT) and then subsequently disrupted by addition of a potent antagonist (e.g. 10µM bicalutamide).

如果你對Chromotek/F2H®-Kit Androgen Receptor感興趣,想了解更詳細(xì)的產(chǎn)品信息,填寫下表直接與廠家聯(lián)系:

留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說明:

  • 驗(yàn)證碼:

    請輸入計(jì)算結(jié)果(填寫阿拉伯?dāng)?shù)字),如:三加四=7
版權(quán)所有 © 2024 蘇州螞蟻淘生物科技有限公司  ICP備案號:蘇ICP備17049038號-2
在線留言 聯(lián)系方式 二維碼

服務(wù)熱線

18915418616

掃一掃,關(guān)注我們

女的被弄到高潮娇喘喷水视频| 豆国产96在线 | 亚洲| 亚洲av永久纯肉无码精品动漫| 亚洲裸男gv网站| 十八岁以下禁止观看黄下载链接 | 性xxxx18免费观看视频| 浓毛老太交欧美老妇热爱乱| 内谢少妇xxxxx8老少交| 久久超碰97人人做人人爱| 亚洲精品无码你懂的| 亚洲国产精品无码专区| 国产精品国产三级在线专区 | 亚洲精品无码久久久久秋霞 | 男女一边摸一边做爽爽的免费阅读| 牲欲强的熟妇农村老妇女| 久久久婷婷五月亚洲97号色| 免费a级毛片在线播放不收费| 久久久噜噜噜久久| 欧美 丝袜 自拍 制服 另类| 无码人妻丰满熟妇精品区| 无码午夜成人1000部免费视频 | 日日噜噜夜夜狠狠久久丁香五月| 国产免费久久精品国产传媒| 成人日韩熟女高清视频一区| 天堂а√在线中文在线| 欧美老妇与禽交| 亚洲av无码一区二区乱子伦| 天堂√最新版中文在线天堂 | 777爽死你无码免费看一二区| 大地资源网最新在线播放| 无码av免费毛片一区二区| 99久久人妻精品免费二区| 亚洲美女色禁图| 欲妇荡岳丰满少妇岳| 婷婷五月综合激情| 欧美成a人片在线观看久| 精品久久久久久| 人妻洗澡被强公日日澡电影| 一边摸一边做爽的视频17国产| 亚洲免费观看在线视频| 熟妇人妻中文av无码|